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ACTN2 Produits

(Actinin, alpha 2 (ACTN2))
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq, Jul 2008].

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Catégories ACTN2 en vedette

ACTN2 Anticorps

High quality antibodies with extensive validation data.

ACTN2 Kits ELISA

Reliable ELISA kits for a wide range of species.

ACTN2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ACTN2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, ICC, IHC (p)
Validations
  • (1)
  • (7)
N° du produit ABIN2855582
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, StM
Validations
  • (6)
N° du produit ABIN6940980
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, StM
Validations
  • (6)
N° du produit ABIN6940979
Quantité 100 μg
Fiche technique Fiche technique

ACTN2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964557
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953409
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN510358
Quantité 96 tests
Fiche technique Fiche technique

ACTN2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3130051
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3088293
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7390205
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ACTN2

Meyers, Heitzman, Krebsbach, Aufdembrink, Hughes, Bartolomucci, Townsend: "Acute AT1R blockade prevents isoproterenol-induced injury in mdx hearts." dans: Journal of molecular and cellular cardiology, Vol. 128, pp. 51-61, (2019) (PubMed).

Chopra, Kutys, Zhang, Polacheck, Sheng, Luu, Eyckmans, Hinson, Seidman, Seidman, Chen: "Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions." dans: Developmental cell, Vol. 44, Issue 1, pp. 87-96.e5, (2018) (PubMed).

Roberts, Romero, Mobley, Mumford, Roberson, Haun, Vann, Osburn, Holmes, Greer, Lockwood, Parry, Kavazis: "Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training." dans: PeerJ, Vol. 6, pp. e5338, (2018) (PubMed).

Liu, Wang, Zhang: "Composite poly(lactic acid)/chitosan nanofibrous scaffolds for cardiac tissue engineering." dans: International journal of biological macromolecules, Vol. 103, pp. 1130-1137, (2017) (PubMed).

Chang, Zhang, Lihua, Feng: "T3 inhibits the calcification of vascular smooth muscle cells and the potential mechanism." dans: American journal of translational research, Vol. 8, Issue 11, pp. 4694-4704, (2016) (PubMed).

Yuan, Liu, Li, Li, Sun, Xu, Man, Fu: "Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiation and ultrastructure processes." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 7, pp. 3957-65, (2015) (PubMed).

Chen, Rao, Wei, Xu, Dong: "Expression patterns of sarcomeric ?-actin, ?-actinin and UCP2 in the myocardium of Kunming mice after exposure to c-terminal polypeptide of cardiotrophin-1." dans: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 6, pp. 796-800, (2014) (PubMed).

Xiao, Wang, Zhang, Bai, Shen: "Similar to spironolactone, oxymatrine is protective in aldosterone-induced cardiomyocyte injury via inhibition of calpain and apoptosis-inducing factor signaling." dans: PLoS ONE, Vol. 9, Issue 2, pp. e88856, (2014) (PubMed).

Xiao, Zhang, Wang, Xu, Yu, Shen: "Activation of an apoptotic signal transduction pathway involved in the upregulation of calpain and apoptosis-inducing factor in aldosterone-induced primary cultured cardiomyocytes." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 53, pp. 364-70, (2013) (PubMed).

Li, Shang: "Inhaled corticosteroids inhibit substance P receptor expression in asthmatic rat airway smooth muscle cells." dans: BMC pulmonary medicine, Vol. 12, pp. 79, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à ACTN2

actinin alpha 2 (actn2), actinin alpha 2 (ACTN2), actinin alpha 2 (Actn2), actinin, alpha 2b (actn2b), actinin alpha 2 S homeolog (actn2.S), 1110008F24Rik, ACTN2, CMD1AA, MGC89234, wu:fd44c03, zgc:123223

Protein level used designations for ACTN2

  • actinin, alpha 2
  • alpha 2 actinin
  • alpha-actinin-2-like
  • F-actin cross-linking protein
  • alpha-actinin skeletal muscle
  • alpha-actinin-2
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