ACVRL1 Produits
(Activin A Receptor Type II-Like 1 (ACVRL1))
Catégories
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008].
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Catégories ACVRL1 en vedette
ACVRL1 Anticorps
High quality antibodies with extensive validation data.
ACVRL1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ACVRL1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ACVRL1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (4)
- (5)
N° du produit
ABIN392241
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, FACS
Validations
- (7)
N° du produit
ABIN3029853
Quantité
0.4 mL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7183058
Quantité
100 μL
Fiche technique
Fiche technique
ACVRL1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953428
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5510685
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5510686
Quantité
96 tests
Fiche technique
Fiche technique
ACVRL1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273821
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
N° du produit
ABIN7320736
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305819
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ACVRL1
: "Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis. ..." dans: Nature metabolism, Vol. 1, Issue 9, pp. 912-926, (2019) (PubMed).: "Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro." dans: Cellular signalling, Vol. 28, Issue 9, pp. 1252-61, (2017) (PubMed).
: "The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes." dans: Cellular & molecular biology letters, Vol. 19, Issue 4, pp. 659-74, (2014) (PubMed).
: "Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90." dans: Journal of cellular physiology, Vol. 227, Issue 2, pp. 759-71, (2011) (PubMed).
: "Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis." dans: The Journal of experimental medicine, Vol. 207, Issue 1, pp. 85-100, (2010) (PubMed).
: "ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 23, Issue 6, pp. 896-906, (2008) (PubMed).
: "LC-MS/MS analysis of apical and basolateral plasma membranes of rat renal collecting duct cells." dans: Molecular & cellular proteomics : MCP, Vol. 5, Issue 11, pp. 2131-45, (2006) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "The activin receptor-like kinase 1 gene: genomic structure and mutations in hereditary hemorrhagic telangiectasia type 2." dans: American journal of human genetics, Vol. 61, Issue 1, pp. 60-7, (1997) (PubMed).
: "Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2." dans: Nature genetics, Vol. 13, Issue 2, pp. 189-95, (1996) (PubMed).
Synonymes et noms alternatifs relatifs à ACVRL1
activin A receptor like type 1 (ACVRL1), activin A receptor type II-like 1 (ACVRL1), activin A receptor like type 1 (acvrl1), activin A receptor like type 1 (Acvrl1), activin A receptor, type II-like 1 (Acvrl1), ACVRL1, ACVRLK1, Acvrlk1, AI115505, AI427544, ALK-1, alk1, ALK1, Alk1, HHT, HHT2, hm:zehn1109, ORW2, R-3, R3, SETHKIR, SKR3, TSR-I, vgb, zehn1109Protein level used designations for ACVRL1
- activin A receptor type II-like 1
- serine/threonine-protein kinase receptor R3
- serine/threonine-protein kinase receptor R3-like
- activin receptor-like kinase 1
- vbg
- violet beauregarde
- TGF-B superfamily receptor type I
- activin A receptor, type II-like kinase 1
- Activin receptor like kinase 1
- SKR3
- TSR-I
- ALK-1
- activin receptor-like kinase-1
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