This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008].
ADAM17
Origine: Humain
Hôte: Mammalian Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM17
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM17
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Wang, Huang, Nayak, Matthews, Warburton, Shi, Sanchez-Esteban: "Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin ?6?1-ADAM17/tumor necrosis factor-?-converting enzyme (TACE) signaling pathway." dans: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25646-57, (2013) (PubMed).
Pseudonymes pour ADAM17 Protéines
ADAM metallopeptidase domain 17 (ADAM17) Protéines a disintegrin and metallopeptidase domain 17 (Adam17) Protéines ADAM metallopeptidase domain 17b (adam17b) Protéines ADAM metallopeptidase domain 17 L homeolog (adam17.L) Protéines ADAM metallopeptidase domain 17 (Adam17) Protéines ADAM metallopeptidase domain 17a (adam17a) Protéines adam17 Protéines ADAM18 Protéines adam18 Protéines CD156B Protéines CD156b Protéines cd156b Protéines CSVP Protéines csvp Protéines fc20b01 Protéines NISBD Protéines si:dkey-81b15.2 Protéines TACE Protéines Tace Protéines tace Protéines wu:fc20b01 Protéines zgc:63886 Protéines