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ADAMTS5 Produits

(ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5))
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq, Jul 2008].

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Catégories ADAMTS5 en vedette

ADAMTS5 Anticorps

High quality antibodies with extensive validation data.

ADAMTS5 Kits ELISA

Reliable ELISA kits for a wide range of species.

ADAMTS5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ADAMTS5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (4)
N° du produit ABIN3016806
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7436774
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN2854716
Quantité 100 μL
Fiche technique Fiche technique

ADAMTS5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
N° du produit ABIN6953465
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953466
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rabbit
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953468
Quantité 96 tests
Fiche technique Fiche technique

ADAMTS5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305905
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3089638
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3130640
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ADAMTS5

Wang, Ye, Ye, Wang, Liu, Jiang, Xu, Zhang, Chen, Wan: "ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease." dans: Disease markers, Vol. 2019, pp. 6129748, (2020) (PubMed).

Yilmaz, Melekoglu, Taskapan, Olmez Budak, Toprak: "The investigation of serum levels of ADAMTS 5 and 8 (the A disintegrin and metalloproteinase with thrombospondin motifs) in the etiology of endometrial cancer." dans: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 40, Issue 6, pp. 856-859, (2020) (PubMed).

Si, Yang, Li, Tian, Zhou, Li, Huang, Kang, Yang, Zhou, Cheng, Shen: "miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence." dans: Molecular therapy. Nucleic acids, Vol. 19, pp. 15-30, (2019) (PubMed).

Tajima, Sekimoto, Yamaguchi, Taniguchi, Kurogi, Maruyama, Chosa: "Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage." dans: BMC musculoskeletal disorders, Vol. 18, Issue 1, pp. 449, (2018) (PubMed).

Huang, Song, Li, Xiao, Chen, Gong, Zeng, Yang, Chen: "Pellet coculture of osteoarthritic chondrocytes and infrapatellar fat pad-derived mesenchymal stem cells with chitosan/hyaluronic acid nanoparticles promotes chondrogenic differentiation." dans: Stem cell research & therapy, Vol. 8, Issue 1, pp. 264, (2018) (PubMed).

Mao, Wu, Zhang, Zhang, Liao, Li, Kang: "MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 1, pp. 38-52, (2018) (PubMed).

Si, Zeng, Liu, Zhou, Chen, Cheng, Lu, Shen: "Intra-articular injection of microRNA-140 (miRNA-140) alleviates osteoarthritis (OA) progression by modulating extracellular matrix (ECM) homeostasis in rats." dans: Osteoarthritis and cartilage, Vol. 25, Issue 10, pp. 1698-1707, (2018) (PubMed).

Mern, Tschugg, Hartmann, Thomé et al.: "Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new ..." dans: PLoS ONE, Vol. 12, Issue 2, pp. e0172181, (2017) (PubMed).

Pérez-García, Carrión, Gutiérrez-Cañas, González-Álvaro, Gomariz, Juarranz: "VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts." dans: Journal of cellular and molecular medicine, Vol. 20, Issue 4, pp. 678-87, (2016) (PubMed).

Serra, Gallelli, Butrico, Buffone, Caliò, De Caridi, Massara, Barbetta, Amato, Labonia, Mimmi, Iaccino, de Franciscis: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." dans: International wound journal, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5), ADAM metallopeptidase with thrombospondin type 1 motif 5 (adamts5), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (Adamts5), 9530092O11Rik, ADAM-TS5, ADAM-TS 5, ADAM-TS 11, ADAMTS-5, ADAMTS-11, ADAMTS1, ADAMTS11, ADMP-2, AI481094, ASMP-2

Protein level used designations for ADAMTS5

  • ADAM metallopeptidase with thrombospondin type 1 motif, 5
  • a disintegrin and metalloproteinase with thrombospondin motifs 5-like
  • A disintegrin and metalloproteinase with thrombospondin motifs 5
  • ADAM-TS 5
  • ADAMTS-5
  • ADMP-2
  • aggrecanase-2
  • implantin
  • a disintegrin and metalloproteinase with thrombospondin motifs 11
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
  • ADAM-TS5
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
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