AKR1C1 Produits
(Dihydrodiol Dehydrogenase (DDH))
Catégories
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008].
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Catégories AKR1C1 en vedette
AKR1C1 Anticorps
High quality antibodies with extensive validation data.
AKR1C1 Kits ELISA
Reliable ELISA kits for a wide range of species.
AKR1C1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
AKR1C1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IHC (p), IF, ICC
Validations
- (3)
- (8)
N° du produit
ABIN2856139
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (2)
N° du produit
ABIN560581
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (3)
N° du produit
ABIN514922
Quantité
100 μL
Fiche technique
Fiche technique
AKR1C1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966360
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4881783
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6385539
Quantité
96 tests
Fiche technique
Fiche technique
AKR1C1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122663
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344752
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344754
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits AKR1C1
: "The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer." dans: Theranostics, Vol. 10, Issue 5, pp. 2188-2200, (2020) (PubMed).: "Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism." dans: Frontiers in physiology, Vol. 10, pp. 833, (2019) (PubMed).
: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." dans: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).
: "Cisplatin resistance in human cervical, ovarian and lung cancer cells." dans: Cancer chemotherapy and pharmacology, Vol. 75, Issue 6, pp. 1217-27, (2015) (PubMed).
: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." dans: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).
: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." dans: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." dans: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells." dans: Oncogene, Vol. 27, Issue 13, pp. 1916-29, (2008) (PubMed).
: "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease." dans: The European journal of neuroscience, Vol. 11, Issue 6, pp. 1988-94, (1999) (PubMed).
: "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting." dans: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31633-6, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à AKR1C1
aldo-keto reductase family 1 member C1 (AKR1C1), aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1), 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBABProtein level used designations for AKR1C1
- 20 alpha-hydroxysteroid dehydrogenase
- 20-alpha-hydroxysteroid dehydrogenase
- aldo-keto reductase C
- aldo-keto reductase family 1 member C1
- chlordecone reductase homolog HAKRC
- dihydrodiol dehydrogenase 1
- dihydrodiol dehydrogenase 1/2
- dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase
- dihydrodiol dehydrogenase isoform DD1
- hepatic dihydrodiol dehydrogenase
- high-affinity hepatic bile acid-binding protein
- indanol dehydrogenase
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
- type II 3-alpha-hydroxysteroid dehydrogenase
- 20-alpha-HSD
- aldo-keto reductase family 1 member C1 homolog
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