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AKT2 Produits

(V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Catégories

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008].

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Catégories AKT2 en vedette

AKT2 Anticorps

High quality antibodies with extensive validation data.

AKT2 Kits ELISA

Reliable ELISA kits for a wide range of species.

AKT2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

AKT2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (7)
N° du produit ABIN513224
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (9)
N° du produit ABIN950116
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (5)
N° du produit ABIN391023
Quantité 400 μL
Fiche technique Fiche technique

AKT2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971094
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971093
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960411
Quantité 96 tests
Fiche technique Fiche technique

AKT2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (3)
N° du produit ABIN5624569
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5569766
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125675
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits AKT2

Li, Kang, Yin, Li, Chen, Li, Zhang, Qiu: "Ginsenoside Rh2 inhibits human A172 glioma cell proliferation and induces cell cycle arrest status via modulating Akt signaling pathway." dans: Molecular medicine reports, Vol. 17, Issue 2, pp. 3062-3068, (2018) (PubMed).

Karaczyn, Adams, Cheng, Matluk, Verdi: "Human NUMB6 Induces Epithelial-Mesenchymal Transition and Enhances Breast Cancer Cells Migration and Invasion." dans: Journal of cellular biochemistry, (2016) (PubMed).

Riquelme, Behrens, Lin, Simon, Papadimitrakopoulou, Izzo, Moran, Kalhor, Lee, Minna, Wistuba: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." dans: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).

Lin, Chen, Liang, Tan: "Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathway." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14294-304, (2016) (PubMed).

Jiang, Zhang, Kang, Wang, Zhang, Chen: "Celecoxib reverts oxaliplatin-induced neuropathic pain through inhibiting PI3K/Akt2 pathway in the mouse dorsal root ganglion." dans: Experimental neurology, Vol. 275 Pt 1, pp. 11-6, (2016) (PubMed).

Sun, Zhang, Wang, Jin, Jia, Yu, Chen: "MiRNA-615-5p functions as a tumor suppressor in pancreatic ductal adenocarcinoma by targeting AKT2." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0119783, (2015) (PubMed).

Cui, Lin, Zuo, Zhang, Dong, Hu, Luo, Chen, Lu: "AKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo." dans: OncoTargets and therapy, Vol. 8, pp. 1681-90, (2015) (PubMed).

Gezginci-Oktayoglu, Sacan, Bolkent, Ipci, Kabasakal, Sener, Yanardag: "Chard (Beta vulgaris L. var. cicla) extract ameliorates hyperglycemia by increasing GLUT2 through Akt2 and antioxidant defense in the liver of rats." dans: Acta histochemica, Vol. 116, Issue 1, pp. 32-9, (2014) (PubMed).

Kuo, Lin, Huo, Su, Yang, Hsiao, Chiang, Chung, Wang, Chang, Chen, Chuu: "Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling." dans: International journal of molecular sciences, Vol. 14, Issue 5, pp. 8801-17, (2013) (PubMed).

Lin, Lin, Hsiao, Wang, Jiang, Hsu, Jim, Chen, Kung, Chuu: "Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells." dans: PLoS ONE, Vol. 8, Issue 12, pp. e82625, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à AKT2

AKT serine/threonine kinase 2 (AKT2), v-akt murine thymoma viral oncogene homolog 2 (akt2), thymoma viral proto-oncogene 2 (Akt2), AKT serine/threonine kinase 2 (Akt2), v-akt murine thymoma viral oncogene homolog 2 L homeolog (akt2.L), 2410016A19Rik, AKT2, akt2-a, AW554154, cb945, HIHGHH, PKB, pkbb, PKBB, pkbbeta, PKBbeta, PKBBETA, pkbss, prkbb, PRKBB, rac-beta, RAC-BETA, v-akt2

Protein level used designations for AKT2

  • v-akt murine thymoma viral oncogene homolog 2
  • RAC-beta serine/threonine-protein kinase
  • AKT2 kinase
  • RAC-beta serine/threonine-protein kinase-like
  • serine/threonine protein kinase
  • PKB beta
  • RAC-PK-beta
  • RAC-beta serine/threonine protein kinase
  • protein kinase Akt-2
  • protein kinase B beta
  • protein kinase B, beta
  • murine thymoma viral (v-akt) homolog-2
  • rac protein kinase beta
  • RAC protein kinase beta RAC-PK beta
  • murine thymoma viral (v-akt) oncogene homolog 2
  • thymoma viral proto-oncogene 2
  • PKB beta-A
  • RAC-PK-beta-A
  • RAC-beta serine/threonine-protein kinase A
  • protein kinase Akt-2-A
  • protein kinase B, beta-A
  • protein kinase B
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