AKR1C2 Produits
(Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
Catégories
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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Catégories AKR1C2 en vedette
AKR1C2 Anticorps
High quality antibodies with extensive validation data.
AKR1C2 Kits ELISA
Reliable ELISA kits for a wide range of species.
AKR1C2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
AKR1C2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN7265549
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, StM
Validations
- (5)
N° du produit
ABIN6939232
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
N° du produit
ABIN560582
Quantité
50 μL
Fiche technique
Fiche technique
AKR1C2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6953599
Quantité
96 tests
Fiche technique
Fiche technique
AKR1C2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121783
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344756
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344758
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits AKR1C2
: "Aldo-keto reductase and sorbitol dehydrogenase enzymes in Egyptian diabetic patients with and without proliferative diabetic retinopathy." dans: Clinical & experimental optometry, Vol. 96, Issue 3, pp. 303-9, (2013) (PubMed).: "Proteomics-based identification of secreted protein dihydrodiol dehydrogenase 2 as a potential biomarker for predicting cisplatin efficacy in advanced NSCLC patients." dans: Lung cancer (Amsterdam, Netherlands), Vol. 77, Issue 2, pp. 427-32, (2012) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." dans: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis." dans: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 217-26, (2011) (PubMed).
: "Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 6, pp. 991-4, (2008) (PubMed).
: "Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis." dans: Toxicology, Vol. 244, Issue 2-3, pp. 257-70, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à AKR1C2
aldo-keto reductase family 1 member C2 (AKR1C2), aldo-keto reductase family 1, member C2 (Akr1c2), AKR1C-pseudo, Akr1c21, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8Protein level used designations for AKR1C2
- 3-alpha-HSD3
- DD-2
- DD/BABP
- aldo-keto reductase family 1 member C2
- chlordecone reductase homolog HAKRD
- dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III
- pseudo-chlordecone reductase
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
- type II dihydrodiol dehydrogenase
- 17-alpha-HSD
- 17-alpha-hydroxysteroid dehydrogenase
- 3(or 17)-alpha-hydroxysteroid dehydrogenase
- 3-alpha-hydroxysteroid dehydrogenase
- aldo-keto reductase family 1 member C21
- aldo-keto reductase family 1, member C21
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