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Integrin beta 3 anticorps (PE)

ITGB3 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal VIPL2 PE
N° du produit ABIN1027701
  • Antigène Voir toutes Integrin beta 3 (ITGB3) Anticorps
    Integrin beta 3 (ITGB3)
    Reactivité
    • 179
    • 94
    • 58
    • 17
    • 15
    • 13
    • 12
    • 10
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    Humain, Non-Human Primate
    Hôte
    • 118
    • 65
    • 13
    • 2
    • 2
    Souris
    Clonalité
    • 112
    • 86
    Monoclonal
    Conjugué
    • 102
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Integrin beta 3 est conjugé à/à la PE
    Application
    • 129
    • 88
    • 51
    • 50
    • 31
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    • 21
    • 15
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    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody VIPL2 recognizes an extracellular epitope of CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
    Réactivité croisée (Details)
    Human, Non-Human Primates
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Clone
    VIPL2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ITGB3 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Reconstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Barrett, Dai, Gamberg, Gallant, Grant: "Circulating CD14-CD36+ peripheral blood mononuclear cells constitutively produce interleukin-10." dans: Journal of leukocyte biology, Vol. 82, Issue 1, pp. 152-60, (2007) (PubMed).

    Williams, Mondal, Agrawal: "The HIV-1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBP." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 230, Issue 11, pp. 872-84, (2005) (PubMed).

    Mondal, Williams, Ali, Eilers, Agrawal: "The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 230, Issue 9, pp. 631-44, (2005) (PubMed).

    Roberts, Woods, Dale, Van Der Sluijs, Norman: "Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins." dans: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1505-15, (2004) (PubMed).

    Ciarlet, Crawford, Cheng, Blutt, Rice, Bergelson, Estes: "VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment." dans: Journal of virology, Vol. 76, Issue 3, pp. 1109-23, (2002) (PubMed).

    Dzionek, Fuchs, Schmidt, Cremer, Zysk, Miltenyi, Buck, Schmitz: "BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6037-46, (2000) (PubMed).

  • Antigène
    Integrin beta 3 (ITGB3)
    Autre désignation
    CD61 (ITGB3 Produits)
    Synonymes
    anticorps BDPLT16, anticorps BDPLT2, anticorps CD61, anticorps GP3A, anticorps GPIIIa, anticorps GT, anticorps INGRB3, anticorps integrin, anticorps INTB3, anticorps GPIIIA, anticorps cd61, anticorps gp3a, anticorps itgb3, anticorps itgb3.2, anticorps itgb3.1, anticorps integrin subunit beta 3, anticorps integrin beta 3, anticorps integrin subunit beta 3 L homeolog, anticorps integrin beta 3a, anticorps integrin beta 3b, anticorps ITGB3, anticorps Itgb3, anticorps itgb3.L, anticorps itgb3a, anticorps itgb3b
    Sujet
    Integrin subunit beta 3,CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.,integrin beta 3, ITGB3, GP3A
    ID gène
    3690
    UniProt
    P05106
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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