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C3 anticorps (AA 1580-1592)

Verified C3 Reactivité: Humain ELISA, IHC Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN1049512
  • Antigène Voir toutes C3 Anticorps
    C3 (Complement Component 3 (C3))
    Épitope
    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1580-1592
    Reactivité
    • 88
    • 54
    • 34
    • 5
    • 4
    • 4
    • 3
    • 3
    Humain
    Hôte
    • 68
    • 42
    • 27
    • 8
    • 7
    • 5
    Chèvre
    Clonalité
    • 122
    • 34
    Polyclonal
    Conjugué
    • 66
    • 24
    • 23
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp C3 est non-conjugé
    Application
    • 102
    • 48
    • 37
    • 34
    • 33
    • 29
    • 29
    • 27
    • 22
    • 17
    • 13
    • 12
    • 12
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Fonction
    complement C3 (aa1580-1592)
    Séquence
    QQRTFISPIK CRE
    Specificité
    This antibody is expected to recognize the C3 alpha chain, C3b alpha' chain and the C3c alpha' chain fragment 2.
    Homologie
    Human
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Classe de qualité
    Verified
    Immunogène
    Peptide with sequence QQRTFISPIKCRE, from the C Terminus of the protein sequence according to NP_000055.2.
    Isotype
    IgG
    Top Product
    Discover our top product C3 Anticorps primaire
  • Indications d'application

    DS WB Results: Preliminary experiments gave an approx 125 kDa band in Human Liver lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 104 kDa according to the largest fragment C3 alpha chain (aa672-1663). Although this fragment is glycosylated, we have not yet found support in the literature for the observed size. The 125 kDa band was successfully blocked by incubation with the immunizing peptide.

    DS IHC Results: Paraffin embedded Human Placenta and Testis. Recommended concentration: 5 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:128000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Minimize freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Antigène
    C3 (Complement Component 3 (C3))
    Autre désignation
    Complement Component 3 (C3 Produits)
    Synonymes
    anticorps AHUS5, anticorps ARMD9, anticorps ASP, anticorps C3a, anticorps C3b, anticorps CPAMD1, anticorps AI255234, anticorps HSE-MSF, anticorps Plp, anticorps C3, anticorps C3-1, anticorps sb:cb26, anticorps si:dkey-76b14.4, anticorps wu:fi34b03, anticorps wu:fj86e11, anticorps C3d, anticorps asp, anticorps cpamd1, anticorps c3, anticorps complement C3, anticorps complement component 3, anticorps complement component c3a, duplicate 1, anticorps complement component 3 L homeolog, anticorps complement component C3, anticorps complement C3-like, anticorps C3, anticorps c3a.1, anticorps c3.L, anticorps LOC443475, anticorps c3, anticorps c3-1, anticorps LOC100060539
    Sujet
    C3, complement component 3, AHUS5, ARMD9, ASP, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, OTTHUMP00000197086, acylation-stimulating protein cleavage product, complement C3, complement component C3
    ID gène
    718
    NCBI Accession
    NP_000055
    Pathways
    Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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