SNCA anticorps (Internal Region)

N° du produit ABIN1049515

Cet anticorps Chèvre Polyclonal détecte spécifiquement SNCA dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SNCA anticorps (Internal Region) (ABIN1049515)

Antigène: SNCA (Synuclein, alpha (SNCA))

Reactivité: Humain, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Classe de qualité: Verified

Détail du produit anti-SNCA anticorps

Épitope: Internal Region

Fonction: Alpha-synuclein

Séquence: ATGFVKKDQL GK

Specificité: This antibody is expected to recognize both reported isoforms (NP_009292.1, NP_000336.1). Reported variants represent identical protein: NP_000336.1, NP_001139527.1, NP_001139526.1

Réactivité croisée: Chien, Humain, Souris, Porc, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-ATGFVKKDQLGK, from the of the protein sequence according to NP_009292.1, NP_000336.1.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry: Paraffin embedded Human Brain (Cerebellum). Recommended concentration: 5 μg/mL.

Western Blot: Approx 17 kDa band observed in Human Brain (Amygdala) and fetal Mouse Brain lysates (calculated MW of 14.5 kDa according to Human NP_000336.1 and Mouse NP_033247.1). This molecular weight is routinely observed by other sources. Recommended co

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: SNCA

Sujet: SNCA, synuclein, alpha (non A4 component of amyloid precursor), NACP, PARK1, PARK4, PD1, alpha-synuclein, non A-beta component of AD amyloid, synuclein alpha-140

ID gène: 6622, 20617, 29219

NCBI Accession: NP_009292, NP_000336

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity