HNRNPA1 anticorps

N° du produit ABIN108609

Cet anticorps anti-HNRNPA1 est un anticorps Souris Monoclonal détectant HNRNPA1 dans WB, ELISA, IF, IP, ICC, IHC (p) et FACS. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 10+ publications.

Aperçu rapide pour HNRNPA1 anticorps (ABIN108609)

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HNRNPA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 9H10

Détail du produit anti-HNRNPA1 anticorps

Purification: Protein A

Immunogène: Full length hnRNP-A1 native protein (partially purified) from HeLa cells (human)

Isotype: IgG2b

Information d'application

Indications d'application: Optimal antibody dilution should be determined by titration, however as a guideline try,Flow Cyt: Use 1 μg for 106 cells.IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval before commencing with IHC staining protocolWB: Use at 1:2000-1:4000. Detects a band of approximately 34 kDa (predicted molecular weight: 38 kDa)IP: Use at an assay dependent dilution. This antibody does not IP the hnRNP complex

Commentaires:

Myeloma, fusion partners: Balb/c Sp2/0 cell line

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-HNRNPA1 (ABIN108609)

Woolley, Algie, Samuel, Harfoot, Wiles, Hung, Tan, Hains, Valova, Huschtscha, Royds, Perez, Yoon, Cohen, Robinson, Bay, Lasham, Braithwaite: "Prognostic association of YB-1 expression in breast cancers: a matter of antibody." dans: PLoS ONE, Vol. 6, Issue 6, pp. e20603, (2011) (PubMed).

Beauchamp, Nassif, Hillock, van der Giessen, von Roretz, Jasmin, Gallouzi: "The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation." dans: Cell death and differentiation, Vol. 17, Issue 10, pp. 1588-99, (2010) (PubMed).

Read, Digard: "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export." dans: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1290-301, (2010) (PubMed).

Rosenberger, De-Castro Arce, Langbein, Steenbergen, Rösl: "Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 7006-11, (2010) (PubMed).

Sellier, Rau, Liu, Tassone, Hukema, Gattoni, Schneider, Richard, Willemsen, Elliott, Hagerman, Charlet-Berguerand: "Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients." dans: The EMBO journal, Vol. 29, Issue 7, pp. 1248-61, (2010) (PubMed).

Kocgozlu, Lavalle, Koenig, Senger, Haikel, Schaaf, Voegel, Tenenbaum, Vautier: "Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells." dans: Journal of cell science, Vol. 123, Issue Pt 1, pp. 29-39, (2009) (PubMed).

Lieberthal, Kaminsky, Parkhurst, Tanese: "The role of YY1 in reduced HP1alpha gene expression in invasive human breast cancer cells." dans: Breast cancer research : BCR, Vol. 11, Issue 3, pp. R42, (2009) (PubMed).

Kashima, Rao, David, Manley: "hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing." dans: Human molecular genetics, Vol. 16, Issue 24, pp. 3149-59, (2007) (PubMed).

van der Giessen, Gallouzi: "Involvement of transportin 2-mediated HuR import in muscle cell differentiation." dans: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2619-29, (2007) (PubMed).

Burd, Dreyfuss: "RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing." dans: The EMBO journal, Vol. 13, Issue 5, pp. 1197-204, (1994) (PubMed).

Détails sur HNRNPA1

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Autre désignation: hnRNP A1 

Sujet: Synonyms:
HNRNPA 1 antibody,Helix destabilizing protein antibody,Helix-destabilizing proteinantibody,Heterogeneous nuclear ribonucleoprotein A1 antibody,Heterogeneous nuclear ribonucleoprotein A1B proteinantibody,Heterogeneous nuclear ribonucleoprotein B2 protein antibody,Heterogeneous nuclear ribonucleoprotein coreprotein A1 antibody,hnRNP A1 antibody,hnRNP core protein A1 antibody,HNRNPA1 antibody,HNRPA1antibody,MGC102835 antibody,Nuclear ribonucleoprotein particle A1 protein antibody,ROA1_HUMANantibody

ID gène: 3178, 15382

OMIM: 164017

UniProt: P09651, P49312