CEACAM1/5 anticorps

N° du produit ABIN108735

Détail du produit anti-CEACAM1/5 anticorps

Antigène: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1/5 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Cell-ELISA (cELISA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Anti-human CEACAM1, 5 (BGP, CEA, CD66a,e)

Purification: Protein G

Immunogène: immunisation with extracted protein of CEACAM5

Clone: 4-3-17

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 Western blot: 4 µg/mL
Immunohistology: 1-2 µg/10^6 cells (on cryosections)
For each application a titration should be performed to determine the optimal concentration.

Commentaires:

Synonyms: CD66ae, BGP, CEA

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: short term: 2 °C - 8 °C, long term: -20 °C

Détails sur CEACAM1/5

Antigène: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Autre désignation: CEACAM1,5 (CEACAM1/5 Produits)

Synonymes: anticorps CD66e, anticorps CEA, anticorps carcinoembryonic antigen related cell adhesion molecule 5, anticorps CEACAM5

Sujet: Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

UniProt: P06731, P13688