Recombinant CEACAM1/5 anticorps (AA 35-433)

N° du produit ABIN7455139

Détail du produit anti-CEACAM1/5 anticorps

Antigène: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Type d'anticorp: Recombinant Antibody

Épitope: AA 35-433

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1/5 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-CEACAM1/5 Recombinant Monoclonal Antibody [BLR032F]

Immunogène: residues 35-433 (ECD)

Clone: BLR032F

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CEACAM1/5

Antigène: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Autre désignation: CEACAM1/5 (CEACAM1/5 Produits)

Synonymes: anticorps CD66e, anticorps CEA, anticorps carcinoembryonic antigen related cell adhesion molecule 5, anticorps CEACAM5

Sujet: Background: Carcinoembryonic antigen related cell adhesion molecules 1 and 5 (CEACAM1 and CEACAM5) are members of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. CEACAM1 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM5 is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, CEACAM5 may regulate differentiation, apoptosis, and cell polarity.

ID gène: 634, 1048

NCBI Accession: NP_001020083

UniProt: P13688, P06731