TWIST1 anticorps (AA 9-74)

N° du produit ABIN1098133

Cet anticorps Souris Monoclonal détecte spécifiquement TWIST1 dans ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour TWIST1 anticorps (AA 9-74) (ABIN1098133)

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TWIST1 est non-conjugé

Application: ELISA

Clone: 2F8E7

Détail du produit anti-TWIST1 anticorps

Épitope: AA 9-74

Fonction: TWIST1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TWIST1 (AA: 9-74) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-TWIST1 (ABIN1098133)

Yu, Li, Lu, Tian, Ma, Wang, Xu: "Down-regulation of TWIST decreases migration and invasion of laryngeal carcinoma Hep-2 cells by regulating the E-cadherin, N-cadherin expression." dans: Journal of cancer research and clinical oncology, Vol. 137, Issue 10, pp. 1487-93, (2011) (PubMed).

Casas, Kim, Bendesky, Ohno-Machado, Wolfe, Yang: "Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis." dans: Cancer research, Vol. 71, Issue 1, pp. 245-54, (2011) (PubMed).

Détails sur TWIST1

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Autre désignation: TWIST1

Sujet: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Poids moléculaire: 21 kDa

ID gène: 7291

UniProt: Q15672

Pathways: Signalisation p53, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity