APOA5 anticorps

N° du produit ABIN1105412

L’anticorps anti-APOA5 Monoclonal Souris est utilisé pour la détection de APOA5 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour APOA5 anticorps (ABIN1105412)

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APOA5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 1G5G9 (c)

Détail du produit anti-APOA5 anticorps

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 0.03 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur APOA5

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Autre désignation: Apolipoprotein A V (ApoA V)

Sujet: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70 % lowerconcentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.Synonyms: APOA5, Apo-AV, ApoA-V, Apolipoprotein A-V, RAP3, Regeneration-associated protein 3

ID gène: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism