Cité dans 1 publication.
Cet anticorps anti-CCL5 Polyclonal Lapin (ABIN110550) détecte spécifiquement CCL5 dans WB.
L’anticorps est réactif avec des échantillons de Rat.
Adamus, Manczak, Machnicki: "Expression of CC chemokines and their receptors in the eye in autoimmune anterior uveitis associated with EAE." dans: Investigative ophthalmology & visual science, Vol. 42, Issue 12, pp. 2894-903, (2001) (PubMed).
Antigène
CCL5
(Chemokine (C-C Motif) Ligand 5 (CCL5))
Autre désignation
RANTES (Regulated Upon Activation Normal T-Cell Expressed And Secreted)
Sujet
RANTES (regulated upon activation, normal T-cell expressed and secreted) is a 70-amino acid CC chemokine originally cloned from T cell-specific sequences-enriched cDNA libraries1 ,2,3. Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T cells and eosinophils, as well as an activator of basophils for histamine release4. In contrast to other CC chemokines, RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases2.