MAP3K14 anticorps

N° du produit ABIN110581

Détail du produit anti-MAP3K14 anticorps

Antigène: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K14 est non-conjugé

Application: Western Blotting (WB)

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: 4 °C

Détails sur MAP3K14

Antigène: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Autre désignation: NIK (NF-kB-Inducing Kinase) (MAP3K14 Produits)

Synonymes: anticorps FTDCR1B, anticorps HS, anticorps HSNIK, anticorps NIK, anticorps F23F1.4, anticorps F23F1_4, anticorps mitogen-activated protein kinase kinase kinase 14, anticorps Nik, anticorps aly, anticorps mitogen-activated protein kinase kinase kinase 14, anticorps MAP3K14, anticorps Map3k14, anticorps MAPKKK14

Sujet: NIK (NF-. B-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-. B activity. NIK, initially isolated from a human B cell cDNA library, contains 795 amino acids with an apparent molecular weight of slightly more than 97 kDa on SDS gel. NIK is a serine/threonine kinase and its kinase activity contributes to I. B phosphorylation. The carboxyl terminal segment of NIK binds TRAF2. A mutant NIK with intact carboxyl terminus but without the two lysine residues at its catalytic domain serves as a dominant-negative inhibitor for NF-. B activation. NIK also interacts with TRAF6 and mediates IL-1-induced NF-. B activation.

Pathways: Signalisation NF-kappaB, TCR Signaling