P-Selectin anticorps (PE)

N° du produit ABIN1106513

L’anticorps Souris Monoclonal anti-P-Selectin a été validé pour FACS. Il convient pour détecter P-Selectin dans des échantillons de Humain et Singe.

Aperçu rapide pour P-Selectin anticorps (PE) (ABIN1106513)

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Selectin est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: AK-6

Détail du produit anti-P-Selectin anticorps (PE)

Specificité: This antibody recognises the CD62P cell surface antigen.

Purification: Affinity Chromatography on Protein G

Immunogène: Human platelet membrane glycoproteins.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water.

Buffer: PBS, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at 2-8 °C.

Détails sur P-Selectin

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Autre désignation: CD62P / P-Selectin

Sujet: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster. The antigen is expressed in the surface of activated platelets and also on endothelial cells both of blood and lymph vessels.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

ID gène: 6403

NCBI Accession: NP_002996

UniProt: P16109