C5 anticorps

N° du produit ABIN1106794

Cet anticorps Lapin Polyclonal détecte spécifiquement C5 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour C5 anticorps (ABIN1106794)

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-C5 anticorps

Specificité: This antibody detects C5.

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Protein A

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Autre désignation: Complement C5

Sujet: C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5a induces smooth muscle contraction, increases vascular permeability, causes degranulation of mast cells and basophils, and release of lysosomal enzymes. In addition C5a stimulates the directed migration of neutrophils, eosinophils, basophils and monocytes. Studies indicate the modulation of the acute-phase response in liver and an overall immune response by inducing synthesis of cytokines such as TNF-alpha, IL-1beta, IL-6 and IL-8. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CPAMD4, Complement component 5

ID gène: 15139

NCBI Accession: NP_034536

UniProt: P06684

Pathways: Système du Complément, Carbohydrate Homeostasis