Glypican 3 anticorps
Aperçu rapide pour Glypican 3 anticorps (ABIN1107403)
Antigène
Voir toutes Glypican 3 (GPC3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes Glypican-3 / GPC3.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
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Purification
- Purified
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.05 % Sodium Azide, 0.5 % protein
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Glypican 3 (GPC3)
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Autre désignation
- Glypican-3 / GPC3
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Sujet
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5
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Poids moléculaire
- 65.5 kDa
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ID gène
- 2719
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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