JUP anticorps (N-Term)

N° du produit ABIN1107898

Cet anticorps Lapin Polyclonal détecte spécifiquement JUP dans WB, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour JUP anticorps (N-Term) (ABIN1107898)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-JUP anticorps

Épitope: N-Term

Specificité: This antibody detects Junction plakoglobin at N-term. No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence at the N-terminal of human Cateningamma .Remarks: Sequence is identical to the related mouse and rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: Junction Plakoglobin

Sujet: Junction Plakoglobin (JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.Synonyms: CTNNG, Catenin gamma, DP3, Desmoplakin III, Desmoplakin-3, JUP

ID gène: 3728

NCBI Accession: NP_002221

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location