Lamin B1 anticorps (C-Term)

N° du produit ABIN1108013

L’anticorps Lapin Polyclonal anti-Lamin B1 a été validé pour WB, IP, IF, IHC (p) et IHC (fro). Il convient pour détecter Lamin B1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Lamin B1 anticorps (C-Term) (ABIN1108013)

Antigène: Lamin B1 (LMNB1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Lamin B1 anticorps

Épitope: C-Term

Specificité: This antibody detects Lamin Beta at C-term. No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence at the C-terminal of human Lamin B .Remarks: Sequence is different from the related rat and mouse sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Lamin B1

Antigène: Lamin B1 (LMNB1)

Autre désignation: Lamin-B1 (LMNB1)

Sujet: Lamins are the major components of the nuclear lamina which underlies the nuclear envelope of eukaryotic cells. lamin B is a structural component of the long-sought-after spindle matrix that promotes microtubule assembly and organization in mitosis. Inspection of the deduced amino acid sequence of lamin B revealed the presence in coil 1B of the alpha-helical domain of a leucine heptad repeat region.Lamin B assembled into a matrix-like network in mitosis through a process that depended on the presence of the guanosine triphosphate-bound form of the small guanosine triphosphatase Ran.Synonyms: LMN2, LMNB, Lamin B1, Lamin B1/B2, Lamin B2

ID gène: 4001

NCBI Accession: NP_005564

UniProt: P20700

Pathways: Apoptose, Caspase Cascade in Apoptosis