PRG2 anticorps

N° du produit ABIN110842

Cet anticorps Souris Monoclonal détecte spécifiquement PRG2 dans WB, IHC (p), IHC (fro) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour PRG2 anticorps (ABIN110842)

Antigène: PRG2 (Bone Marrow Proteoglycan (PRG2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: BMK13

Détail du produit anti-PRG2 anticorps

Specificité: Specific for eosinophil major basic protein irrespective of the stages of eosinophil activation and can be regarded as an eosinophil marker. The antibody will recognize the 23.8 kDa secreted pro-form of MBP (Pregnancy associated MBP) and the 13.8 kDa mature form found in the matrix of the eosinophil large specific granule. Does not cross-react with horse, mouse or rat MBP.

Purification: Protein A chromatography

Isotype: IgG1

Information d'application

Indications d'application: IHC with fresh frozen tissue (fix in methanol: acetone)IHC with formalin fixed paraffin-embedded tissue (treat with 0.1 % trypsin before blocking)Western blotELISA
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS with 0.09 % sodium azide as preservative and 0.1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur PRG2

Antigène: PRG2 (Bone Marrow Proteoglycan (PRG2))

Autre désignation: Proteoglycan 2

Sujet: PRG2 is a cytotoxin and helminthotoxin. It also induces noncytolytic histamine release from human basophils and is involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg.Synonyms: BMPG, Bone marrow proteoglycan, EMBP, Eosinophil granule major basic protein, PRG2, Pregnancy-associated major basic protein

ID gène: 5553

NCBI Accession: NP_002719

UniProt: P13727