PPP2R4 anticorps
Aperçu rapide pour PPP2R4 anticorps (ABIN1108715)
Antigène
Voir toutes PPP2R4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts to PPP2R4.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Purified
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0,05 % sodium azide, 0,5 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
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Autre désignation
- PPP2R4 / PTPA
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Sujet
- Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.Synonyms: PP2A subunit B' PR53 isoform, Phosphotyrosyl phosphatase activator, Serine/threonine-protein phosphatase 2A regulatory subunit B'
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Poids moléculaire
- 41 kDa
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ID gène
- 5524
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Pathways
- Signalisation PI3K-Akt, M Phase, Hepatitis C, Toll-Like Receptors Cascades
Antigène
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