PPP2R4 anticorps (C-Term)

N° du produit ABIN6264394

Détail du produit anti-PPP2R4 anticorps

Antigène: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: PPP2R4 Antibody detects endogenous levels of total PPP2R4.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PPP2R4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PPP2R4

Antigène: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Autre désignation: PTPA (PPP2R4 Produits)

Synonymes: anticorps PP2A, anticorps PR53, anticorps PTPA, anticorps 2610042B21Rik, anticorps C77440, anticorps N28142, anticorps PTPRA, anticorps Ppp2r4, anticorps fc23d07, anticorps ppp2r4, anticorps wu:fc23d07, anticorps zgc:92766, anticorps pp2a, anticorps ppp2r4.L, anticorps pr53, anticorps ptpa, anticorps protein phosphatase 2 phosphatase activator, anticorps protein phosphatase 2 protein activator, anticorps protein phosphatase 2 phosphatase activator L homeolog, anticorps PTPA, anticorps Ptpa, anticorps ptpa, anticorps ptpa.L

Sujet:

Description: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg2+ (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg2+ (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis, the function appears to be independent from PP2A.

Gene: PTPA

Poids moléculaire: 40kDa

ID gène: 5524

UniProt: Q15257

Pathways: Signalisation PI3K-Akt, M Phase, Hepatitis C, Toll-Like Receptors Cascades