Cet anticorps anti-S100A9 Monoclonal Souris (Clone 1H9) (ABIN1108926) détecte spécifiquement S100A9 dans WB et EIA.
L’anticorps est réactif avec des échantillons de Humain.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
0.1 mg/mL
Buffer
PBS, 0.02 % Sodium Azide, 0.1 % BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store at 2 - 8 °C.
Antigène
S100A9
(S100 Calcium Binding Protein A9 (S100A9))
Autre désignation
S100A9 / Calgranulin-B / MRP14
Sujet
The calcium-binding, migration inhibitory factor-related proteins, MRP-8 (S100A8) and MRP-14 (S100A9) belong to the S100 protein family. The expression of these proteins is largely confined to the cytosol of neutrophils and monocytes. The complex formation of these proteins is a calcium-dependent process. The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60 % of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. In inflammatory conditions small venueles stain with both anti-S100A8 and S100A9. The staining of the two subunits is always coincident. The S100A8/A9 complex has antibacterial, antifungal and immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils.Synonyms: CAGB, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, MRP-14, Migration inhibitory factor-related protein 14, S100 calcium-binding protein A9, S100-A9