Tumor Protein p73 anticorps (C-Term)

N° du produit ABIN1109413

Cet anticorps Lapin Polyclonal détecte spécifiquement Tumor Protein p73 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Tumor Protein p73 anticorps (C-Term) (ABIN1109413)

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tumor Protein p73 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Tumor Protein p73 anticorps

Épitope: C-Term

Specificité: This antibody detects Tumor protein p73 (alpha) at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogène: A peptide mapping at the C-terminal end of human P73a .Remarks: Sequence differs from the related rat sequence by single amino acid.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Tumor Protein p73

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Sujet: P73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation. Moreover, p73 was phosphorylated in vivo in response to ionizing radiation. p73, a member of the p53 family of tumour-suppressor proteins, can also induce apoptosis.p73 gene is mapped to chromosome 1p36. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.Synonyms: p53-like transcription factor, p53-related protein

ID gène: 7161

NCBI Accession: NP_001119712

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus