Lamin A/C anticorps

N° du produit ABIN1110152

L’anticorps Souris Monoclonal anti-Lamin A/C a été validé pour WB et IF. Il convient pour détecter Lamin A/C dans des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Porc.

Aperçu rapide pour Lamin A/C anticorps (ABIN1110152)

Antigène: Lamin A/C (LMNA)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lamin A/C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Lamin A/C anticorps

Purification: purified

Immunogène: Purified, full length E. Coli derived recombinant human HSP27 protein.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur Lamin A/C

Antigène: Lamin A/C (LMNA)

Autre désignation: Lamin A/C

Sujet: The heat shock proteins were discovered, as the name suggests, since they are heavily upregulated when cells are stressed by temperatures above the normal physiological range. They are expressed in unstressed cells also and have a normal function as chaperones, helping other proteins to fold correctly, and are required in much greater amounts if the cell or tissue is stressed by heat. The increased levels are generated transcriptionally under the influence of a powerful transcription factor, the heat shock factor 1 (HSF1). The different heat shock proteins were originally named based on their SDS-PAGE mobility, so HSP27 has an an apparent molecular weight of 27 kDa.

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus