IGF1 anticorps

N° du produit ABIN111026

Détail du produit anti-IGF1 anticorps

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF1 est non-conjugé

Application: Radioimmunoassay (RIA), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: The basic IGF-1-like forms (pI>9.0) showed substantial cross-reactivity, as did Rat and Mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in-vitro bioassays for insulin-like, mitogenic and sulphation activities. Cross-reactivity: ILGF-1:100 % ILGF-2:1 % Proinsulin: 1.4 % MSF: 1 % Insulin: < 0.1 %.Aff. Const.:10e8-10e9 l/mole

Purification: Affinity Chromatography on Protein A.

Immunogène: Purified human IGF-1 conjugated to ovalbumin.

Clone: BM23

Isotype: IgG1

Information d'application

Indications d'application: RIA. ELISA. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS buffer with 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IGF1

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Autre désignation: Insulin-Like Growth Factor I / IGF1 (IGF1 Produits)

Synonymes: anticorps IGF-I, anticorps IGF1A, anticorps IGFI, anticorps C730016P09Rik, anticorps Igf-1, anticorps Igf-I, anticorps Npt2B, anticorps IGF-1, anticorps IGFIA, anticorps IGF-IB, anticorps igf1, anticorps IGF-1L, anticorps IGF-1a, anticorps IGF1, anticorps igf-1, anticorps igf1-A, anticorps igf1.S, anticorps xigf1, anticorps insulin like growth factor 1, anticorps insulin-like growth factor 1, anticorps insulin-like growth factor I, anticorps insulin like growth factor 1 L homeolog, anticorps IGF1, anticorps Igf1, anticorps LOC100136741, anticorps igf1, anticorps LOC678666, anticorps igf1.L, anticorps LOC104911603

Sujet: Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.Synonyms: IBP1, IGF-I, MGF, Mechano growth factor, Somatomedin-C

ID gène: 3479

NCBI Accession: NP_000609

UniProt: P05019

Pathways: Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation