ITGA3 anticorps (Isoform 3B, N-Term)

N° du produit ABIN112371

Cet anticorps anti-ITGA3 Monoclonal Souris (Clone 54B3) (ABIN112371) détecte spécifiquement ITGA3 dans WB, IF et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ITGA3 anticorps (Isoform 3B, N-Term) (ABIN112371)

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 54B3

Détail du produit anti-ITGA3 anticorps

Épitope: Isoform 3B, N-Term

Séquence: CTRYYQIMPK YHAVRIREEE RYPPPGSTLP TKK

Specificité: 54B3 recognizes specifically the cytoplasmic domain of integrin subunit a3B which is present in microvascular structures in brain and heart.

Purification: Purified

Immunogène: Synthetic peptide corresponding to a 32 amino acid stretch in the cytoplasmic domain of integrin alpha3B including an appending N-terminal cysteine coupled to keyhole limpet hemocyanin.

Isotype: IgG1

Information d'application

Indications d'application: Immunoblotting (1: 100 - 1: 1000). Immunocytochemistry. Immunohistochemistry on frozen tissues (1: 25 - 1: 200, with avidin-biotinylated horseradishperoxidase complex (ABC) as detection reagent).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ITGA3

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Autre désignation: CD49c / ITGA3

Sujet: Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated α and β subunits. More than 18 α and 8 β subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits α3 and α6, two cytoplasmic variants, A and B, have been identified.Synonyms: CD49 antigen-like family member C, FRP-2, GAPB3, Galactoprotein B3, ITGA-3, ITGAG3, Integrin alpha-3, MSK18, VLA-3 alpha chain, VLA3

ID gène: 3675

NCBI Accession: NP_002195

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex