beta-2 Microglobulin anticorps (Biotin)

N° du produit ABIN112398

Cet anticorps anti-beta-2 Microglobulin est un anticorps Souris Monoclonal détectant beta-2 Microglobulin dans WB, FACS, IP, IHC (p), RIA et EIA. Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour beta-2 Microglobulin anticorps (Biotin) (ABIN112398)

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta-2 Microglobulin est conjugé à/à la Biotin

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

Clone: B2M-01

Détail du produit anti-beta-2 Microglobulin anticorps (Biotin)

Specificité: The antibody reacts with Beta-2-microglobulin (b2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble Beta-2-microglobulin.

Réactivité croisée (Details): Species reactivity (tested):Human.

Immunogène: Purified Human Beta-2-microglobulin

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry (1/200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-beta-2 Microglobulin (Biotin) (ABIN112398)

Poláková, Železníková, Russ: "HLA-G5 in the blood of leukemia patients and healthy individuals." dans: Leukemia research, Vol. 37, Issue 2, pp. 139-45, (2013) (PubMed).

Khurana, Traum, Aivado, Wells, Guerrero, Grall, Libermann, Schachter: "Urine proteomic profiling of pediatric nephrotic syndrome." dans: Pediatric nephrology (Berlin, Germany), Vol. 21, Issue 9, pp. 1257-65, (2006) (PubMed).

Lafon, Prehaud, Megret, Lafage, Mouillot, Roa, Moreau, Rouas-Freiss, Carosella: "Modulation of HLA-G expression in human neural cells after neurotropic viral infections." dans: Journal of virology, Vol. 79, Issue 24, pp. 15226-37, (2005) (PubMed).

Détails sur beta-2 Microglobulin

Antigène: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Autre désignation: beta-2-Microglobulin

Sujet: B2M is a 12 kDa Ig like glycoprotein. It non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin

ID gène: 567

NCBI Accession: NP_004039

UniProt: P61769

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process