C3 anticorps
Aperçu rapide pour C3 anticorps (ABIN113307)
Antigène
Voir toutes C3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody is specific for human C3d and gave a single arc in the alpha region when tested by IEP against aged human plasma (C3d) and a contiuous double arc in the alpha and beta regions when tested against fresh human plasma (C3 and C3d).
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Purification
- Ion exchange chromatography
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Immunogène
- Purified C3d from pooled activated serum
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Indications d'application
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ELISA. Radial Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Glycine buffered saline, containing 0.09 % Sodium Azide (NaN3), 0.09 % EACA, 0.01 % Benzamidine and 1 mM EDTA
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Agent conservateur
- Sodium azide, Benzamidine, EACA
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Précaution d'utilisation
- This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- C3 (Complement Component 3 (C3))
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Autre désignation
- Complement C3
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Sujet
- The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
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ID gène
- 718
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NCBI Accession
- NP_000055
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UniProt
- P01024
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Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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