CDK1 anticorps

N° du produit ABIN114583

Cet anticorps Souris Monoclonal détecte spécifiquement CDK1 dans WB, IF, IP et IHC (p). Il présente une réactivité avec des échantillons de Humain et Boeuf (Vache).Il a été cité dans 1 publication.

Aperçu rapide pour CDK1 anticorps (ABIN114583)

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivité: Humain, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: POH-1

Détail du produit anti-CDK1 anticorps

Specificité: The antibody POH-1 specifically detects Cdk1 (p34Cdc2). Staining of Cdk1 reflects the proliferating potential of respective tissue.

Réactivité croisée (Details): Species reactivity (tested):Human, Non-Human Primates, Bovine.

Purification: Affinity Chromatography on Protein A.

Immunogène: Recombinant human cdc2 protein.

Isotype: IgG2a

Information d'application

Indications d'application: Western Blot. Immunoprecipitation. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-CDK1 (ABIN114583)

Jaeger, Koczan, Thiesen, Ibrahim, Gross, Spang, Kunz: "Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 3, pp. 806-15, (2007) (PubMed).

Détails sur CDK1

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Autre désignation: CDK1

Sujet: The p34cdc2 is a 34 kDa phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. Expression of p34cdc2 reflects the proliferating potential of positively staining tissue. The maximal activity of p34cdc2 is achieved when it is fully dephosphorylated. It is a 34kD catalytic subunit of maturation promoting factor (MPF) and complexes with both cyclin A and cyclin B in mammalian cells.Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase

ID gène: 983

NCBI Accession: NP_001777

UniProt: P06493

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA