TEK anticorps (Extracellular Domain)

N° du produit ABIN115157

Détail du produit anti-TEK anticorps

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Épitope: Extracellular Domain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TEK est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificité: This monoclonal antibody will detect native Human TIE-2/tek in ELISA experiments and on the surface of different Human cell types.

Purification: Affinity Chromatography on Protein G

Immunogène: Recombinant Human soluble extracellular TIE-2.

Clone: Cl-9

Isotype: IgG1

Information d'application

Indications d'application: Suitable for ELISA (1-15 μg/mL), Western blot (1-2 μg/mL), FACS and cell sorting (2-5 μg/mL) .
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: PBS, pH 7.4 without preservatives or stabilizers

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TEK

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Autre désignation: CD202b / TEK (TEK Produits)

Synonymes: anticorps TEK, anticorps DKFZp469E064, anticorps AA517024, anticorps Cd202b, anticorps Hyk, anticorps Tie2, anticorps tie-2, anticorps CD202B, anticorps TIE-2, anticorps TIE2, anticorps VMCM, anticorps VMCM1, anticorps Tie-2, anticorps tie2, anticorps TEK receptor tyrosine kinase, anticorps angiopoietin-1 receptor, anticorps TEK tyrosine kinase, endothelial, anticorps TEK, anticorps LOC100408334, anticorps tek, anticorps Tek

Sujet: TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

ID gène: 7010

NCBI Accession: NP_000450

UniProt: Q02763

Pathways: Signalisation RTK, Growth Factor Binding