KIT anticorps (C-Term)

N° du produit ABIN115378

Cet anticorps Lapin Polyclonal détecte spécifiquement KIT dans IHC (p). Il présente une réactivité avec des échantillons de Humain et Chien.

Aperçu rapide pour KIT anticorps (C-Term) (ABIN115378)

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIT est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KIT anticorps

Épitope: C-Term

Specificité: This antibody reacts with a 145 kDa protein. This antibody can be used in the identification of gastrointestinal stromal tumors.
Cellular Localization: Cell membrane, cytoplasm.

Purification: Purified

Immunogène: A synthetic peptide from c-terminus of Human CD117/c-kit protein.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Embedded Sections: Use 1/50-1/100 diluted antibody inan ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur KIT

Antigène: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Autre désignation: CD117 / C-Kit

Sujet: C-kits is expressed in many tissues and cells. c-kits is involved in the development of several lineages of stem cells, such as germ cells, neural crest derived melanocytes and hematopoietic precursor cells. This antibody can be used in the identification of gastrointestinal stromal tumors.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR

ID gène: 3815

NCBI Accession: NP_000213

UniProt: P10721

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity