LYVE1 anticorps (AA 24-231)

N° du produit ABIN115663

Cet anticorps Lapin Polyclonal détecte spécifiquement LYVE1 dans WB, FACS, IHC (p), EIA et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour LYVE1 anticorps (AA 24-231) (ABIN115663)

Antigène: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LYVE1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-LYVE1 anticorps

Épitope: AA 24-231

Specificité: This antibody will detect LYVE-1 on the surface of lymphatic endothelial cells by Immunohistochemistry. It detects a 70 kDa LYVE-1 band in Western blotting. This antibody is not reactive with Mouse LYVE-1.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Antigen Affinity Chromatography

Immunogène: Highly pure recombinant Human soluble LYVE-1 produced in insect cells. It consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis).

Information d'application

Indications d'application: Immunohistochemistry on Frozen and Paraffin Embedded Sections (1-5 μg/mL). Heat mediated antigen retrieval is recommended when staining paraffin embeddedsections. Western blot (1-2 μg/mL). ELISA (1-15 μg/mL). Flow Cytometry (3-20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL

Buffer: 5 mM PBS, pH 7.2 without preservatives or stabilizers

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. Protect from Light!

Détails sur LYVE1

Antigène: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Autre désignation: LYVE-1

Sujet: LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosamino-glycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1

ID gène: 10894

NCBI Accession: NP_006682

UniProt: Q9Y5Y7

Pathways: Glycosaminoglycan Metabolic Process