NAMPT anticorps (Biotin)
Aperçu rapide pour NAMPT anticorps (Biotin) (ABIN1169029)
Antigène
Voir toutes NAMPT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes human, mouse and rat Nampt.
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Réactivité croisée
- Humain, Souris, Rat (Rattus)
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant human Nampt (visfatin/PBEF).
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Agent conservateur
- Without preservative
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Date de péremption
- 12 months
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- NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
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Autre désignation
- Nampt (Visfatin/PBEF)
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Sujet
- Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52 kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
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UniProt
- P43490
Antigène
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