NAMPT anticorps (AA 301-400)

N° du produit ABIN727100

Détail du produit anti-NAMPT anticorps

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Épitope: AA 301-400

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAMPT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Pig,Horse,Chicken,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PBEF

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NAMPT

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Autre désignation: PBEF1 (NAMPT Produits)

Synonymes: anticorps 1110035O14Rik, anticorps PBEF, anticorps PBEF1, anticorps VF, anticorps VISFATIN, anticorps AI314458, anticorps AI480535, anticorps NAmPRTase, anticorps Pbef, anticorps Pbef1, anticorps Visfatin, anticorps visfatin, anticorps pbef, anticorps pbef1, anticorps nicotinamide phosphoribosyltransferase, anticorps Nicotinamide phosphoribosyltransferase, anticorps nicotinamide phosphoribosyltransferase S homeolog, anticorps NAMPT, anticorps Nampt, anticorps nampt, anticorps Smon_0680, anticorps Mrub_2845, anticorps Cseg_3704, anticorps BC1002_3997, anticorps Ftrac_2686, anticorps Varpa_5681, anticorps Celal_3900, anticorps Deima_0880, anticorps BC1001_3724, anticorps Celly_1696, anticorps Clole_1542, anticorps Tsp_05934, anticorps nampt.S

Sujet:

Synonyms: VF, PBEF, PBEF1, VISFATIN, 1110035O14Rik, Nicotinamide phosphoribosyltransferase, NAmPRTase, Nampt, Pre-B-cell colony-enhancing factor 1, Pre-B cell-enhancing factor

Background: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

ID gène: 10135

UniProt: P43490