NAMPT anticorps (AA 400-426)

N° du produit ABIN652958

Détail du produit anti-NAMPT anticorps

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Épitope: AA 400-426

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAMPT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NAMPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the Central region of human NAMPT.

Clone: RB22920

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-NAMPT (ABIN652958)

Zhang, Tong, Huang: "Nicotinamide phosphoribosyl transferase (Nampt) is a target of microRNA-26b in colorectal cancer cells." dans: PLoS ONE, Vol. 8, Issue 7, pp. e69963, (2013) (PubMed).

Pittelli, Formentini, Faraco, Lapucci, Rapizzi, Cialdai, Romano, Moneti, Moroni, Chiarugi: "Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool." dans: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 34106-14, (2010) (PubMed).

Détails sur NAMPT

Antigène: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Autre désignation: NAMPT (NAMPT Produits)

Synonymes: anticorps 1110035O14Rik, anticorps PBEF, anticorps PBEF1, anticorps VF, anticorps VISFATIN, anticorps AI314458, anticorps AI480535, anticorps NAmPRTase, anticorps Pbef, anticorps Pbef1, anticorps Visfatin, anticorps visfatin, anticorps pbef, anticorps pbef1, anticorps nicotinamide phosphoribosyltransferase, anticorps Nicotinamide phosphoribosyltransferase, anticorps nicotinamide phosphoribosyltransferase S homeolog, anticorps NAMPT, anticorps Nampt, anticorps nampt, anticorps Smon_0680, anticorps Mrub_2845, anticorps Cseg_3704, anticorps BC1002_3997, anticorps Ftrac_2686, anticorps Varpa_5681, anticorps Celal_3900, anticorps Deima_0880, anticorps BC1001_3724, anticorps Celly_1696, anticorps Clole_1542, anticorps Tsp_05934, anticorps nampt.S

Sujet: NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Poids moléculaire: 55521

ID gène: 10135

NCBI Accession: NP_005737

UniProt: P43490