SIRT1 anticorps

N° du produit ABIN1169086

Cet anticorps Lapin Polyclonal détecte spécifiquement SIRT1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SIRT1 anticorps (ABIN1169086)

Antigène: SIRT1 (Sirtuin 1 (SIRT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SIRT1 anticorps

Fonction: anti-Sirtuin 1 (human), pAb

Specificité: Recognizes human sirtuin 1. Detects a band of ~78 kDa by Western blot.

Attributs du produit: Polyclonal Antibody. Recognizes human sirtuin 1. Detects a band of ~78 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin-1 is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. Sirtuin-1 emerged as critical regulator of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Sirtuin-1 has been suggested as potential biomarker for tumorigenesis.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human sirtuin 1.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détails sur SIRT1

Antigène: SIRT1 (Sirtuin 1 (SIRT1))

Autre désignation: Sirtuin 1

Sujet:

Alternate Names/Synonyms: SIRT1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like Protein 1, SIR2L1

Product Description: Sirtuin-1 is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. Sirtuin-1 emerged as critical regulator of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Sirtuin-1 has been suggested as potential biomarker for tumorigenesis.

UniProt: Q96EB6

Pathways: Signalisation MAPK, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling