SIRT1 anticorps
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- Antigène Voir toutes SIRT1 Anticorps
- SIRT1 (Sirtuin 1 (SIRT1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIRT1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- Recognizes human sirtuin 1. Detects a band of ~78 kDa by Western blot.
- Réactivité croisée
- Humain
- Stérilité
- 0.2 μm filtered
- Immunogène
- Recombinant human sirtuin 1.
- Top Product
- Discover our top product SIRT1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Agent conservateur
- Without preservative
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Date de péremption
- 6 months
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- Antigène
- SIRT1 (Sirtuin 1 (SIRT1))
- Autre désignation
- Sirtuin 1 (SIRT1 Produits)
- Synonymes
- anticorps sirtuin 1, anticorps AA673258, anticorps SIR2L1, anticorps Sir2, anticorps Sir2a, anticorps Sir2alpha, anticorps sir2l1, anticorps sirtuin, anticorps SIR2, anticorps sirtuin 1, anticorps sirtuin 1 L homeolog, anticorps SIRT1, anticorps SRT1, anticorps Sirt1, anticorps sirt1.L
- Sujet
- Sirtuin-1 is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. Sirtuin-1 emerged as critical regulator of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Sirtuin-1 has been suggested as potential biomarker for tumorigenesis.
- UniProt
- Q96EB6
- Pathways
- Signalisation MAPK, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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