Leptin anticorps
Aperçu rapide pour Leptin anticorps (ABIN1169150)
Antigène
Voir toutes Leptin (LEP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- anti-Leptin (rat), pAb
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Specificité
- Recognizes rat leptin. Weakly cross-reacts with human and mouse leptin. Detects a band of ~16 kDa by Western blot.
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Réactivité croisée (Details)
- Weakly cross-reacts with human and mouse leptin.
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Attributs du produit
- Polyclonal Antibody. Recognizes rat leptin. Weakly cross-reacts with human and mouse leptin. Detects a band of ~16 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Leptin is involved in the signaling pathway that regulates the size of the body fat depot. An increase in the level of leptin may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Defects in the leptin gene may be a cause of autosomal recessive obesity.
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant rat leptin.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Date de péremption
- 6 months
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- Leptin (LEP)
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Autre désignation
- Leptin
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Sujet
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Alternate Names/Synonyms: OB Gene Product, Obese Factor
Product Description: Leptin is involved in the signaling pathway that regulates the size of the body fat depot. An increase in the level of leptin may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Defects in the leptin gene may be a cause of autosomal recessive obesity.
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UniProt
- P50596
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Pathways
- Signalistation JAK/STAT, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
Antigène
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