ARHGEF7 anticorps

N° du produit ABIN1169227

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGEF7 dans WB, ELISA et ICC. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.Il a été cité dans 1 publication.

Aperçu rapide pour ARHGEF7 anticorps (ABIN1169227)

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-ARHGEF7 anticorps

Fonction: anti-beta-Pix (mouse), pAb

Specificité: Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix.

Réactivité croisée (Details): Cross-reacts with human and rat beta-Pix.

Attributs du produit: Polyclonal Antibody. Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix. Source: Rabbit. Applications: ELISA, ICC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant beta-Pix SH3 domain.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Références pour anticorps anti-ARHGEF7 (ABIN1169227)

Oh, Yoo, Jo, Song, Kim, Park: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." dans: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).

Détails sur ARHGEF7

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Autre désignation: beta-Pix

Sujet:

Alternate Names/Synonyms: ARHGEF7, Rho Guanine Nucleotide Exchange Factor 7, PAK-interacting Exchange Factor beta, p85SPR, COOL-1

Product Description: beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.

UniProt: Q9ES28

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation