ARHGEF7 anticorps (AA 654-688)

N° du produit ABIN6242820

Détail du produit anti-ARHGEF7 anticorps

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Épitope: AA 654-688

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF7 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ARHGEF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 654-688 amino acids from human ARHGEF7.

Clone: RB56222

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur ARHGEF7

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Autre désignation: ARHGEF7 (ARHGEF7 Produits)

Synonymes: anticorps BETA-PIX, anticorps COOL-1, anticorps COOL1, anticorps Nbla10314, anticorps P50, anticorps P50BP, anticorps P85, anticorps P85COOL1, anticorps P85SPR, anticorps PAK3, anticorps PIXB, anticorps cool1, anticorps p50, anticorps p85, anticorps pak3, anticorps pixb, anticorps ARHGEF7, anticorps P85spr, anticorps Pak3bp, anticorps Cool, anticorps PIX, anticorps betaPix, anticorps betaPix-b, anticorps betaPix-c, anticorps cool-1, anticorps mKIAA0142, anticorps p85Cool1, anticorps p85SPR, anticorps arhgef7, anticorps bbh, anticorps bpix, anticorps im:7142367, anticorps wu:fc35h08, anticorps zgc:101775, anticorps Rho guanine nucleotide exchange factor 7, anticorps Rho guanine nucleotide exchange factor 7 S homeolog, anticorps ankyrin repeat domain 10, anticorps Rho guanine nucleotide exchange factor (GEF7), anticorps Rho guanine nucleotide exchange factor (GEF) 7b, anticorps ARHGEF7, anticorps arhgef7.S, anticorps arhgef7, anticorps ANKRD10, anticorps Arhgef7, anticorps arhgef7b

Sujet: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Poids moléculaire: 90012

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation