ARHGEF7 anticorps (AA 654-688)
Aperçu rapide pour ARHGEF7 anticorps (AA 654-688) (ABIN6242820)
Antigène
Voir toutes ARHGEF7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 654-688
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Homologie
- M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This ARHGEF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 654-688 amino acids from human ARHGEF7.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
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Autre désignation
- ARHGEF7
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Sujet
- Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
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Poids moléculaire
- 90012
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UniProt
- Q14155
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
Antigène
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