Calreticulin anticorps

N° du produit ABIN1169306

L’anticorps anti-Calreticulin Polyclonal Lapin est utilisé pour la détection de Calreticulin dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour Calreticulin anticorps (ABIN1169306)

Antigène: Calreticulin (CALR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calreticulin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Calreticulin anticorps

Fonction: anti-Calreticulin (human), pAb

Specificité: Recognizes human calreticulin. Detects a band of ~60 kDa by Western blot.

Attributs du produit: Polyclonal Antibody. Recognizes human calreticulin. Detects a band of ~60 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human calreticulin.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détails sur Calreticulin

Antigène: Calreticulin (CALR)

Autre désignation: Calreticulin

Sujet:

Alternate Names/Synonyms: CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60

Product Description: Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response