Calreticulin anticorps
Aperçu rapide pour Calreticulin anticorps (ABIN1169307)
Antigène
Voir toutes Calreticulin (CALR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes human calreticulin.
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Réactivité croisée
- Humain
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant human calreticulin.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Agent conservateur
- Without preservative
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Date de péremption
- 12 months
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- Calreticulin (CALR)
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Autre désignation
- Calreticulin
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Sujet
- Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.
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UniProt
- P27797
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
Antigène
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