Caspase 1 (p10) anticorps (Biotin)

N° du produit ABIN1169387

L’anticorps anti-Caspase 1 (p10) Monoclonal Souris est utilisé pour la détection de Caspase 1 (p10) dans des échantillons de Souris. Il a été validé pour WB.

Aperçu rapide pour Caspase 1 (p10) anticorps (Biotin) (ABIN1169387)

Antigène: Caspase 1 (p10) (CASP-1 (p10))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 1 (p10) est conjugé à/à la Biotin

Application: Western Blotting (WB)

Clone: Casper-2

Détail du produit anti-Caspase 1 (p10) anticorps (Biotin)

Fonction: anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (Biotin)

Specificité: Recognizes endogenous full-length and activated (p10 fragment) mouse caspase-1.

Attributs du produit: Monoclonal Antibody. Recognizes endogenous full-length and activated (p10 fragment) mouse caspase-1. Isotype: Mouse IgG2a. Clone: Casper-2. Applications: WB. Liquid. In PBS containing 0.02 % sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant mouse caspase-1.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur Caspase 1 (p10)

Antigène: Caspase 1 (p10) (CASP-1 (p10))

Autre désignation: Caspase-1 p10

Sujet:

Alternate Names/Synonyms: Interleukin-1beta Convertase, IL-1BC, Interleukin-1beta-converting Enzyme, ICE

Product Description: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.

UniProt: P29452