Cet anticorps anti-FGF19 Monoclonal Souris (Clone FG369-1) (ABIN1169397) détecte spécifiquement FGF19 dans WB, ELISA et IHC.
L’anticorps est réactif avec des échantillons de Humain.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Agent conservateur
Without preservative
Stock
4 °C,-20 °C
Stockage commentaire
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Date de péremption
12 months
Antigène
FGF19
(Fibroblast Growth Factor 19 (FGF19))
Autre désignation
FGF-19
Sujet
FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.