FGF19 anticorps

N° du produit ABIN1169397

Détail du produit anti-FGF19 anticorps

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGF19 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Recognizes human FGF-19. Detects a band of ~25 kDa by Western blot.

Réactivité croisée: Humain

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human FGF-19.

Clone: FG369-1

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur FGF19

Antigène: FGF19 (Fibroblast Growth Factor 19 (FGF19))

Autre désignation: FGF-19 (FGF19 Produits)

Synonymes: anticorps FGF-19, anticorps Fgf15, anticorps fibroblast growth factor 19, anticorps FGF19, anticorps Fgf19, anticorps fgf19

Sujet: FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

UniProt: O95750

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway