Interferon gamma anticorps
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- Antigène Voir toutes Interferon gamma (IFNG) Anticorps
- Interferon gamma (IFNG)
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Interferon gamma est non-conjugé
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Application
- ELISA, Neutralization (Neut), Intracellular Staining (ICS)
- Marque
- BD Pharmingen™
- Attributs du produit
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Neutralization Activity: This antibody has been reported to be useful for the neutralization of mouse IFN-gamma anti-viral activity. Neutralization activity may be measured with a encphalomyocarditis viral (EMCV) resistance assay using 1 ng/mL recombinant mouse IFN-gamma (Cat. No. 554587) with L929 indicator cells.
50% Neutralization (ND50) at 1 - 20 ng/mL
95% Neutralization at 15 - 333 ng/mL - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Immunogène
- Mouse IFN-gamma Recombinant Protein
- Clone
- XMG1-2
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product IFNG Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered.
- Agent conservateur
- Azide free
- Stock
- 4 °C
- Stockage commentaire
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." dans: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).
: "In vivo cytokine production in murine listeriosis. Evidence for immunoregulation by gamma delta+ T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 1, pp. 232-7, (1996) (PubMed).
: "Differential production of interferon-gamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by gamma delta T cells in vivo." dans: Nature, Vol. 373, Issue 6511, pp. 255-7, (1995) (PubMed).
: "Induction of cytokines in mice with parainfluenza pneumonia." dans: Journal of virology, Vol. 69, Issue 2, pp. 1288-91, (1995) (PubMed).
: "Enumeration of IFN-gamma producing lymphocytes by flow cytometry and correlation with quantitative measurement of IFN-gamma." dans: Journal of immunological methods, Vol. 173, Issue 2, pp. 219-28, (1994) (PubMed).
: "Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 3, pp. 1246-53, (1994) (PubMed).
: "A simple, sensitive, dual mAb based ELISA for murine gamma interferon determination: comparison with two common bioassays." dans: Journal of immunoassay, Vol. 14, Issue 3, pp. 129-48, (1993) (PubMed).
: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." dans: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).
: "Rapid, quantitative, semiautomated assay for virus-induced and immune human interferons." dans: Journal of clinical microbiology, Vol. 12, Issue 3, pp. 433-8, (1981) (PubMed).
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Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." dans: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).
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- Antigène
- Interferon gamma (IFNG)
- Autre désignation
- IFN-gamma (IFNG Produits)
- Synonymes
- anticorps IFG, anticorps IFI, anticorps IFN-g, anticorps Ifg, anticorps IFNG2, anticorps IFN-gamma, anticorps IFN-G, anticorps IFNG, anticorps IFNgamma, anticorps TCRalpha, anticorps INF-G, anticorps ifng, anticorps interferon gamma, anticorps interferon, gamma 1-2, anticorps IFNG, anticorps Ifng, anticorps ifng1-2
- Sujet
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The XMG1.2 monoclonal antibody specifically binds to mouse interferon-gamma (IFN-gamma) protein. IFN-gamma is a pleiotropic cytokine, of approximately 15-17 kDa, involved in the regulation of inflammatory and immune responses. It plays an important role in activation, growth, and differentiation of T and B lymphocytes, macrophages, NK cells and other non-hematopoietic cell types. IFN-gamma production is associated with the Th1 cell differentiation. The purified form of this antibody has been reported to be a neutralizing antibody.
Synonyms: IFN-gamma, IFN-g, IFN-gamma, Interferon gamma, Type II Interferon - Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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