CD14 anticorps

N° du produit ABIN1177335

Cet anticorps anti-CD14 est un anticorps Souris Monoclonal détectant CD14 dans FACS et Neut. Adapté pour Humain, Cynomolgus, Macaque rhésus, Babouin et Chien. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CD14 anticorps (ABIN1177335)

Antigène: CD14

Reactivité: Humain, Cynomolgus, Macaque rhésus, Babouin, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Neutralization (Neut)

Clone: M5E2

Détail du produit anti-CD14 anticorps

Marque: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotype: IgG2a kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Références pour anticorps anti-CD14 (ABIN1177335)

Wright, Ramos, Tobias, Ulevitch, Mathison: "CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein." dans: Science (New York, N.Y.), Vol. 249, Issue 4975, pp. 1431-3, (1990) (PubMed).

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: The M5E2 monoclonal antibody specifically binds to CD14, a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
Synonyms: LPS receptor, LPS-R, Myeloid cell-specific leucine-rich glycoprotein

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades