CD3 anticorps
Aperçu rapide pour CD3 anticorps (ABIN1177370)
Antigène
Voir toutes CD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Marque
- BD Pharmingen™
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Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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Isotype
- IgG2a kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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Agent conservateur
- Azide free
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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- CD3
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Autre désignation
- CD3
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Sujet
- Reacts with the human epsilon-chain, a 20 kDa subunit of CD3/T cell antigen receptor complex found on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show this antibody to be mitogenic when used in conjuction with pokeweed mitogen. CD3 plays a role in signal transduction during antigen recognition. HIT3a antibody does not stain intracellular CD3 unlike the other CD3 clone, UCHT1.
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Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
Antigène
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